PLAVIX is a prescription-only medicine that helps keep blood platelets from sticking together and forming clots. PLAVIX is for patients who have had a recent heart attack, a recent stroke, or have poor circulation in the legs (Peripheral Artery Disease). PLAVIX in combination with aspirin is for patients hospitalized with heart-related chest pain or a heart attack. Read Important Safety Information and access US Full Prescribing Information Including BOXED WARNING and Medication Guide.